Newest issue of Game Informer magazine that will hit mailboxes and newsstands in the coming days will feature Mass Effect 3 as it cover story and contains plenty of new details on Bioware's upcoming final installment in the Mass Effect trilogy some of which you can read below or just wait until you get your hands on a copy of Game Informer
No multiplayer confirmed which a kind of a relief for me since the game doesn't need it!
